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Another consequence of needing all RECs associated in multin
2019-04-29
Another consequence of needing all RECs associated in multinational collaborations (even when research will only be done in one LMIC) to review studies is the reinforcement of the perception that RECs from LMIC do not meet international standards. Although some RECs in LMICs have historically had in
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The presence of in the local environment together with the
2019-04-29
The presence of in the local environment, together with the multiple modes of Zika sphingosine 1-phosphate receptor modulator introduction and spread, highlight the urgent need: to (i) develop an active vector surveillance and early Zika virus detection system, (ii) introduce public health awarene
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NASA and the Russian Federal
2019-04-29
NASA and the Russian Federal Space Agency each supply medical equipment for the ISS. NASA\'s medical apparatus is called the crew health care system (CHeCS). The Health Maintenance System (HMS) is one part of the CHeCS. It is an in-flight preventive medical system that can diagnose and treat patient
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Osteosclerosis was also significant at the level of osteobla
2019-04-29
Osteosclerosis was also significant at the level of osteoblastic bone metastases. The effect, in this case, seemed to reach a plateau level since the difference between the 24 and the 12 months time point was not significant in this subgroup. Residual osteoclastic activity is present even in sclerot
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br Bone physiology br Osteolytic bone metastasis the
2019-04-29
Bone physiology Osteolytic bone metastasis: the “Vicious Cycle” Once metastatic cancer cdc42 colonize bone, they do not, on their own, destroy bone. They interact with osteoblasts, the normal bone-forming cells, and osteoclasts to induce massive bone degradation. In turn, bone-derived growth
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Our study also showed that the risk
2019-04-29
Our study also showed that the risk of treatment discontinuation is lower in patients treated in gynecological practices than in those receiving treatment in general practices. In this context, it carboxypeptidase a is worth mentioning that in Germany, gynecologists are customarily responsible for t
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Loss of function mutations in the
2019-04-29
Loss-of-function mutations in the INa channel α-subunit (SCN5A) is the most common (~20%) etiology of BrS [49]. Recently, SCN10A, a neuronal sodium channel gene encoding Nav1.8 has been identified as a major susceptibility gene (~16%) for BrS [50]. In addition, loss-of-function mutations in the ICa,
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This report should help to
2019-04-29
This report should help to convince policy makers and programme managers worldwide to address this unfinished agenda of targeted HIV prevention. Investments in programmes for key populations and creation of a conducive environment for HIV prevention and human rights can make a great difference to th
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El tema de Cuba por cierto no puede desaparecer
2019-04-29
El tema de Cuba, por cierto, no puede desaparecer de la noche GDC-0994 la mañana de la política estadounidense. Debe tener un proceso para recolocar a los representantes cubano-americanos y en general para que se reacomode el ala más conservadora de la comunidad cubano-americana de Miami. Los anglos
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Evidentemente como corriente socioeclesial heterog
2019-04-29
Evidentemente, como corriente socioeclesial heterogénea, la tl adquirió particularidades en función de los lugares de reflexión y enunciación teológica. Para el caso que concierne hexokinase inhibition este artículo, es importante destacar que en países como Argentina, Nicaragua y El Salvador -donde
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In WHO Task Force on Developing Health Systems Guidance prop
2019-04-29
In 2012, WHO Task Force on Developing Health Systems Guidance proposed a series of processes and tools to support evidence-informed decisions about health system interventions. Many of the processes were adapted from clinical evidence-based medicine and an insightful commentary by Peters and Bennet
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Introduction Atrial fibrillation AF is the
2019-04-28
Introduction Atrial fibrillation (AF) is the most common cardiac arrhythmia, and it commonly occurs after cardiac surgery. AF is often associated with stroke, congestive heart failure, and myocardial infarction, all of which contribute to the increase in the length of hospital stay, higher medical
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In general we measured the
2019-04-28
In general, we measured the GSK2126458 temperatures of 135 acupoints in healthy students. The skin temperatures of these acupoints had consistency at a narrow range of 34.88–36.14°C, but had differences among them arising in part from concentricity distribution to keep whole body warmness. Skin acu
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Sultan et al retrospectively searched the surveillance epide
2019-04-28
Sultan et al retrospectively searched the surveillance, epidemiology, and end results (SEER) database for patients who were diagnosed with NPC from 1988 to 2006. They compared the clinical features and outcomes of 129 children and adolescents (n and young adults compared with older adults with nasop
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As with any open label study
2019-04-28
As with any open-label study, it is possible that a placebo effect may have contributed to patients analgesia after initiation of the therapy. A randomized placebo-controlled trial would be required to finally prove the high analgesic effect of the loading-dose treatment with Ibandronate in metastat
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